Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk
- Creator: Pouget, Jennie G. , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Martin, Javier , Mayes, Maureen D. , Bossini-Castillo, Lara , López-Isac, Elena , Jin, Ying , Santorico, Stephanie A. , Spritz, Richard A. , Hakonarson, Hakon , Polychronakos, Constantin , Raychaudhuri, Soumya , Han, Buhm , Knight, Jo , Cairns, Murray , Henskens, Frans A. , Kelly, Brian J. , Loughland, Carrmel M. , Michie, Patricia T. , Schall, Ulrich A. , Scott, Rodney , Tooney, Paul A. , Wu, Yang , Mignot, Emmanuel , Ollila, Hanna M. , Barker, Jonathan , Spain, Sarah , Dand, Nick , Trembath, Richard
- Resource Type: journal article
- Date: 2019
Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero
- Creator: Warrington, Nicole M. , Shevroja, Enisa , Hemani, Gibran , Hysi, Pirro G. , Jiang, Yunxuan , Auton, Adam , Boer, Cindy G. , Mangino, Massimo , Wang, Carol A. , Kemp, John P. , McMahon, George , Medina-Gomez, Carolina , Hickey, Martha , Trajanoska, Katerina , Wolke, Dieter , Ikram, M. Arfan , The 23and Me Research Team , Montgomery, Grant W. , Felix, Janine F. , Wright, Margaret J. , Pennell, Craig E.
- Resource Type: journal article
- Date: 2018
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
- Creator: de Vries, P. S. , Chasman, D. I. , Hottenga, J. J. , Trompet, S , Müller-Nurasyid, M. , Zhao, J. H. , Brody, J. A. , Kleber, M. E. , Guo, X. , Wang, J. J. , Auer, P. L. , Attia, John R. , Sabater-Lleal, M. , Yanek, L. R. , Ahluwalia, T. S. , Lahti, J. , Venturini, C. , Tanaka, T. , Bielak, L. F. , Joshi, P. K. , Rocanin-Arjo, A. , Kolcic, I. , Navarro, P. , Chen, M. H. , Rose, L. M. , Oldmeadow, Christopher , Riess, H. , Mazur, J. , Basu, S. , Goel, A. , Yang, Q. , Ghanbari, M. , Gonneke, Willemsen , Rumley, A. , Huffman, J. E. , Fiorillo, E. , de Craen, A. J. M. , Grotevendt, A. , Scott, R. , Taylor, K. D. , Delgado, G. E. , Yao, J. , Kifley, A. , Kooperberg, C. , Qayyum, R. , Steri, M. , Lopez, L. , Berentzen, T. L. , Räikkönen, K. , Mangino, M. , Bandinelli, S. , Peyser, P. A. , Wild, S. , Trégouët, D. A. , Wright, A. F. , Marten, J. , Tang, W. , Zemunik, T. , Morrison, A. C. , Sennblad, B. , Tofler, G. , de Maat, M. P. M. , De Geus, E. J. C. , Lowe, G. D. , Zoledziewska, M. , Sattar, N. , Binder, H. , Teumer, A. , Völker, U. , Waldenberger, M. , Khaw, K. T. , Scott, Rodney J. , Marioni, R. E. , Grossmann, V.
- Resource Type: journal article
- Date: 2016
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer
- Creator: Chen, Maxine M. , O'Mara, Tracy A. , Cheng, Timothy H. T. , Cook, Linda S. , Crous-Bou, Marta , Doherty, Jennifer , Friedenreich, Christine M. , Garcia-Closas, Montserrat , Gaudet, Mia M. , Gorman, Maggie , Haiman, Christopher , Hankinson, Susan E. , Thompson, Deborah J. , Holliday, Elizabeth G. , Painter, Jodie N. , Australian National Endometrial Cancer Study Group (ANECS), , Attia, John , Black, Amanda , Brinton, Louise , Chanock, Stephen , Chen, Chu
- Resource Type: journal article
- Date: 2016
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis
- Creator: Gu, Ben J. , Field, Judith , Butzkueven, Helmut , Gresle, Melissa , Laws, Simon M. , Petrou, Steven , Hoffjan, Sabine , Akkad, Denis A. , Graham, Colin A. , Hawkins, Stanley , Glaser, Anna , Bedri, Sahl Khalid , Dutertre, Sébastien , Hillert, Jan , Matute, Carlos , Antiguedad, Alfredo , Wiley, James S. , Ou, Amber , Kilpatrick, Trevor J. , Lechner-Scott, Jeannette , Scott, Rodney , Lea, Rodney , Taylor, Bruce V. , Stankovich, Jim
- Resource Type: journal article
- Date: 2015
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Healey, Catherine S. , Fridley, Brooke L. , Børresen-Dale, Anne-Lise , Kristensen, Vessela N. , Cox, Angela , Swerdlow, Anthony J. , Orr, Nicholas , Bolla, Manjeet K. , Wang, Qin , Palmieri Weber, Rachel , Chen, Zhihua , Kaufmann, Susanne , Shah, Mitul , French, Juliet D. , Pharoah, Paul D. P. , Dunning, Alison M. , Tomlinson, Ian , Easton, Douglas F. , Edwards, Stacey L. , Thompson, Deborah J. , Spurdle, Amanda B. , Hillman, Kristine M. , Walpole, Carina , Moya, Leire , Pollock, Pamela , Jones, Angela , Howarth, Kimberley , Martin, Lynn , Gorman, Maggie , Batra, Jyotsna , Hodgson, Shirley , National Study of Endometrial Cancer Genetics Group (NSECG) , CHIBCHA Consortium , De Polanco, Ma. Magdalena Echeverry , Sans, Monica , Carracedo, Angel , Castellvi-Bel, Sergi , Rojas-Martinez, Augusto , Santos, Erika , Teixeira, Manuel R. , Cheng, Timothy , Carvajal-Carmona, Luis , Shu, Xiao-Ou , Long, Jirong , Zheng, Wei , Xiang, Yong-Bing , The Australian National Endometrial Cancer Study Group (ANECS) , Montgomery, Grant W. , Webb, Penelope M. , Scott, Rodney J. , McEvoy, Mark , Lose, Felicity A. , Attia, John , Holliday, Elizabeth , Martin, Nicholas G. , Nyholt, Dale R. , Henders, Anjali K. , Fasching, Peter A. , Hein, Alexander , Beckmann, Matthias W. , Renner, Stefan P. , Dörk, Thilo , Dennis, Joe , Hillemanns, Peter , Dürst, Matthias , Runnebaum, Ingo , Lambrechts, Diether , Coenegrachts, Lieve , Schrauwen, Stefanie , Amant, Frederic , Winterhoff, Boris , Dowdy, Sean C. , Goode, Ellen L. , Michailidou, Kyriaki , Teoman, Attila , Salvesen, Helga B. , Trovik, Jone , Njolstad, Tormund S. , Werner, Henrica M. J. , Ashton, Katie , Proietto, Tony , Otton, Geoffrey , Tzortzatos, Gerasimos , Mints, Miriam , Tyrer, Jonathan P. , Tham, Emma , RENDOCAS , Hall, Per , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Hopper, John L. , Southey, Melissa C. , Australian Ovarian Cancer Study (AOCS) , Ekici, Arif B. , Ahmed, Shahana , Ruebner, Matthias , Johnson, Nicola , Peto, Julian , Burwinkel, Barbara , Marme, Frederik , Brenner, Hermann , Dieffenbach, Aida K. , Miendl, Alfons , Brauch, Hiltrud , The GENICA Network, , Ferguson, Kaltin , Lindblom, Annika , Depreeuw, Jeroen , Moisse, Matthieu , Chang-Claude, Jenny , Rudolph, Anja , Couch, Fergus J. , Olsen, Janet E. , Giles, Graham G. , Bruinsma, Fiona , Cunnigham, Julie M.
- Resource Type: journal article
- Date: 2015
Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes
- Creator: Oegema, Renske , Cushion, Thomas D. , Dobyns, William B. , Ishak, Gisele E. , Rees, Mark I. , Doherty, Dan , Phelps, Ian G. , Chung, Seo-Kyung , Dempsey, Jennifer C. , Collins, Sarah , Mullins, Jonathan G. L. , Dudding, Tracy , Gill, Harinder , Green, Andrew J.
- Resource Type: journal article
- Date: 2015
Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium
- Creator: Moayyeri, Alireza , Hsu, Yi-Hsiang , Smith, Albert V. , Cooper, Cyrus , Kung, Annie Wai Chee , Lips, Paul , Alen, Markku , Attia, John , Luisa Brandi, Maria , de Groot, Lisette C. P. G. M. , Lehtimäeki, Terho , Riancho, José A. , Campbell, Harry , Pye, Stephen R. , Liu, Yongmei , Harris, Tamara B. , Akesson, Kristina , Karlsson, Magnus , Lee, Jong-Young , Wallaschofski, Henri , Duncan, Emma L. , O'Neill, Terence W. , Gudnason, Vilmundur , Spector, Timothy D. , Leo, Paul J. , Rousseau, François , Orwoll, Eric , Cummings, Steven R. , Wareham, Nick J. , Rivadeneira, Fernando , Uitterlinden, Andre G. , Prince, Richard L. , Kiel, Douglas P. , Reeve, Jonathan , Kaptoge, Stephen K. , Teumer, Alexander , Hwang, Joo-Yeon , Ohlsson, Claes , McGuigan, Fiona , Minster, Ryan L. , Hayward, Caroline , Olmos, José M. , Karasik, David , Lyytikäeinen, Leo-Pekka , Lewis, Joshua R. , Swart, Karin M. A. , Masi, Laura , Oldmeadow, Chris , Holliday, Elizabeth G. , Cheng, Sulin , van Schoor, Natasja M. , Harvey, Nicholas C. , Kruk, Marcin , Estrada, Karol , del Greco M, Fabiola , Igl, Wilmar , Trummer, Olivia , Grigoriou, Efi , Luben, Robert , Liu, Ching-Ti , Zhou, Yanhua , Oei, Ling , Medina-Gomez, Carolina , Zmuda, Joseph , Xiao, Su-Mei , Tranah, Greg , Brown, Suzanne J. , Williams, Frances M. , Soranzo, Nicole , Jakobsdottir, Jphanna , Siggeirsdottir, Kristin , Holliday, Kate L. , Hannemann, Anke , Go, Min Jin , Garcia, Melissa , Nielson, Carrie , Polasek, Ozren , Laaksonen, Marika , Zhu, Kun , Enneman, Anke W. , McEvoy, Mark , Peel, Roseanne , Sham, Pak Chung , Jaworski, Maciej , Johansson, Åsa , Hicks, Andrew A. , Srikanth, Priya , Pludowski, Pawel , Scott, Rodney , Dhonukshe-Rutten, Rosalie A. M. , van der Velde, Nathalie , Käehöenen, Mika , Viikari, Jorma S. , Sieväenen, Harri , Raitakari, Olli T. , González-Macías, Jesús , Hernández, Jose L. , Giroux, Sylvie , Mellströem, Dan , Ljunggren, Östen , Cho, Yoon Shin , Vöelker, Uwe , Nauck, Matthias , Homuth, Georg , Vöelzke, Henry , Haring, Robin , Brown, Matthew A. , McCloskey, Eugene , Wilson, Scott G. , Nicholson, Geoffrey C. , Eastell, Richard , Eisman, John A. , Jones, Graeme , Reid, Ian R. , Dennison, Elaine M. , Wark, John , Boonen, Steven , Vanderschueren, Dirk , Wu, Frederick C. W. , Zheng, Hou-Feng , Aspelund, Thor , Richards, J. Brent , Bauer, Doug , Hofman, Albert , Khaw, Kay-Tee , Dedoussis, George , Obermayer-Pietsch, Barbara , Gyllensten, Ulf , Pramstaller, Peter P. , Lorenc, Roman S.
- Resource Type: journal article
- Date: 2014
Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
- Creator: Purrington, Kristen S. , Slettedahl, Seth , Carpenter, Jane , Ko, Yon-Dschun , Van Deurzen, Carolien H. M. , Martens, John W. M. , Kriege, Mieke , Figueroa, Jonine D. , Chanock, Stephen J. , Lissowska, Jolanta , Tomlinson, Ian , Kerin, Michael J. , Miller, Nicola , Yannoukakos, Drakoulis , Schneeweiss, Andreas , Tapper, William J. , Gerty, Susan M. , Durcan, Lorraine , Mclean, Catriona , Milne, Roger L. , Baglietto, Laura , dos Santos Silva, Isabel , Fletcher, Olivia , Johnson, Nichola , Haiman, Christopher A. , Van'T Veer, Laura J. , Cornelissen, Sten , Försti, Ast , Torres, Diana , Rüdiger, Thomas , Rudolph, Anja , Flesch-Janys, Dieter , Nickels, Stefan , Weltens, Caroline , Floris, Giuseppe , Fasching, Peter A. , Moisse, Matthieu , Dennis, Joe , Wang, Qin , Dunning, Alison M. , Shah, Mitul , Brown, Judith , Simard, Jacques , Anton-Culver, Hoda , Neuhausen, Susan L. , Hopper, John L. , Mannermaa, Arto , Bogdanova, Natalia , Dörk, Thilo , Zheng, Wei , Radice, Paolo , Jakubowska, Anna , Lubinski, Jan , Devillee, Peter , Brauch, Hiltrud , Hooning, Maartje , García-Closas, Montserrat , Winqvist, Robert , Sawyer, Elinor , Burwinkel, Barbara , Marmee, Frederick , Eccles, Diana M. , Giles, Graham G. , Peto, Julian , Schmidt, Marjanka , Broeks, Annegien , Hamann, Ute , Chang-Claude, Jenny , Brenner, Hermann , Lambrechts, Diether , Pharoah, Paul D. P. , Easton, Douglas , Pankratz, V. Shane , Slager, Susan , Vachon, Celine M. , Couch, Fergus J. , Lindblom, Annika , Chenevix-Trench, Georgia , Benitez, Javier , Bolla, Manjeet K. , Swerdlow, Anthony , Kristensen, Vessela , Guénel, Pascal , Meindl, Alfons , Darabi, Hatef , Eriksson, Michael , Fagerholm, Rainer , Aittomäki, Kristiina , Blomqvist, Carl , Nordestgaard, Børge G. , Michailidou, Kyriaki , Nielsen, Sune F. , Flyger, Henrik , Wang, Xianshu , Olswold, Curtis , Olson, Janet E. , Mulligan, Anna Marie , Knight, Julia A. , Tchatchou, Sandrine , Reed, Malcolm W. R. , Cross, Simon S. , Czene, Kamila , Liu, Jianjun , Li, Jingmei , Humphreys, Keith , Clarke, Christine , Scott, Rodney , ABCTB Investigators , Fostira, Florentia , Fountzilas, George , Konstantopoulou, Irene , Henderson, Brian E. , Nevanlinna, Heli , Schumacher, Frederick , Le Marchand, Loic , Ekici, Arif B. , Hartmann, Arndt , Beckmann, Matthias W. , Hartikainen, Jaana M. , Kosma, Veli-Matti , Kataja, Vesa , Jukkola-Vuarinen, Arja , Pylkäs, Katri , Bojesen, Stig E. , Kauppila, Saila , Dieffenbach, Aida Karina , Stegmaier, Christa , Arndt, Volker , Margolin, Sara , Australian Ovarian Cancer Study Group , kConFab Investigators , Balleine, Rosemary , Perez, Jose Ignacio Arias , Zamora, M. Pilar , Andrulis, Irene L. , Menéndez, Primitiva , Ashworth, Alan , Jones, Michael , Orr, Nick , Arveux, Patrick , Kerbrat, Pierre , Truong, Thérèse , Bugert, Peter , Toland, Amanda E. , Ambrosone, Christine B. , Cox, Angela , Labrèche, France , Goldberg, Mark S. , Dumont, Martine , Ziogas, Argyrios , Lee, Eunjung , Dite, Gillian S. , Apicella, Carmel , Southey, Melissa C. , Long, Jirong , Shrubsole, Martha , Hall, Per , Deming-Halverson, Sandra , Ficarazzi, Fiolmena , Barile, Monica , Peterlongo, Paolo , Durda, Katarzyna , Jaworska-Bieniek, Katarzyna , Tollenaar, Robert A. E. M. , Seynaeve, Caroline , The GENICA Network , Brüning, Thomas
- Resource Type: journal article
- Date: 2014
No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis
- Creator: Goris, An , van Setten, Jessica , Diekstra, Frank , Ripke, Stephan , Patsopoulos, Nikolaos A. , Sawcer, Stephen J. , The International Multiple Sclerosis Genetics Consortium , van Es, Michael , The Australia and New Zealand MS Genetics Consortium , Andersen, Peter M. , Melki, Judith , Meininger, Vincent , Hardiman, Orla , Landers, John E. , Brown, Robert H. , Shatunov, Aleksey , Leigh, Nigel , Al-Chalabi, Ammar , Shaw, Christopher E. , Traynor, Bryan J. , Chio, Adriano , Restagno, Gabriella , Mora, Gabriele , Ophoff, Roel A. , Oksenberg, Jorge R. , Van Damme, Philip , Compston, Alastair , Robberecht, Wim , Dubois, Bénédicte , van den Berg, Leonard H. , De Jager, Philip L. , Veldink, Jan H. , de Bakker, Paul I. W.
- Resource Type: journal article
- Date: 2014
The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells
- Creator: Shahijanian, Fernando , Parnell, Grant P. , Baxter, Alan , Kermode, Allan , Carroll, William , Butzkueven, Helmut , Booth, David , Stewart, Graeme , Vucic, Steve , Wiley, James , Field, Judith , Tajouri, Lotti , McKay, Fiona C. , Griffiths, Lyn , Barnett, Michael , Scott, Rodney , Lechner-Scott, Jeannette , Moscato, Pablo , Broadley, Simon , Slee, Mark , Kilpatrick, Trevor , Taylor, Bruce , Charlesworth, Jac , Gatt, Prudence N. , Brown, Matt , Mason, Deborah , Stewart, Graeme J. , Booth, David R. , Shojoei, Maryam , O'Connor, Kate S. , Schibeci, Stephen D. , Brilot, Fabienne , Liddle, Christopher , Batten, Marcel
- Resource Type: journal article
- Date: 2014
Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis
- Creator: Lee, S. Hong , Harold, Denise , Nyholt, Dale R. , Goddard, Michael E. , Zondervan, Krina T. , Williams, Julie , Montgomery, Grant W. , Wray, Naomi R. , Visscher, Peter M.
- Resource Type: journal article
- Date: 2013
Resequencing and fine-mapping of the chromosome 12q13-14 locus associated with multiple sclerosis refines the number of implicated genes
- Creator: Cortes, Adrian , Field, Judith , Glazov, Evgeny A. , Hadler, Johanna , ANZgene Consortium, , Stankovich, Jim , Brown, Matthew A. , Lechner-Scott, Jeannette , Moscato, Pablo
- Resource Type: journal article
- Date: 2013
Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of sertoli cell polarity and spermatogenesis
- Creator: Tanwar, Pradeep S. , Kaneko-Tarui, Tomoko , Zhang, LiHua , Teixeira, Jose M.
- Resource Type: journal article
- Date: 2012
Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks
- Creator: Kerzendorfer, Claudia , Whibley, Annabel , Carpenter, Gillian , Outwin, Emily , Chiang, Shih-Chieh , Turner, Gillian , Schwartz, Charles , El-Khamisy, Sherif , Raymond, F. Lucy , O'Driscoll, Mark
- Resource Type: journal article
- Date: 2010
The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis
- Creator: Gandhi, Kaushal S. , McKay, Fiona C. , Danoy, Patrick , Stewart, Graeme J. , Broadley, Simon , Moscato, Pablo , Lechner-Scott, Jeannette , Scott, Rodney J. , Booth, David R. , ANZgene Multiple Sclerosis Genetics Consortium , Cox, Mathew , Riveros, Carlos , Armstrong, Nicola , Heard, Robert N. , Vucic, Steve , Williams, David W. , Stankovich, Jim , Brown, Matthhew
- Resource Type: journal article
- Date: 2010
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia
- Creator: Beveridge, Natalie J. , Tooney, Paul A. , Carroll, Adam P. , Gardiner, Erin , Bowden, Nikola A. , Scott, Rodney J. , Tran, Nham , Dedova, Irina , Cairns, Murray J.
- Resource Type: journal article
- Date: 2008
Systematic review and meta-analysis of the association between complementary factor HY402H polymorphisms and age-related macular degeneration
- Creator: Thakkinstian, Ammarin , Han, Pearline , McEvoy, Mark , Smith, Wayne , Hoh, Josephine , Magnusson, Kristinn , Zhang, Kang , Attia, John
- Resource Type: journal article
- Date: 2006
SIAH1 targets the alternative splicing factor T-STAR for degradation by the proteasome
- Creator: Venables, Julian P. , Dalgliesh, Caroline , Paronetto, Maria Paolo , Skitt, Lindi , Thornton, Jared K. , Saunders, Philippa T. , Sette, Claudio , Jones, Keith T. , Elliott, David J.
- Resource Type: journal article
- Date: 2004